Following the release of her film “E.T. the Extra-Terrestrial,” 7-year-old Drew Barrymore hosted “Saturday Night Live.” This marked the launch of a decades-long connection with “SNL” and its cast members. Drew would return five more times as host and go on to costar in numerous films alongside former “SNL” cast members. | AARP

Drew Barrymore and I play a giant, royal game of 'Heads Up!' | Ellen DeGeneres

Fred Savage and The Wonder Years ABC's Elisha EJ Williams both had their first kisses on the set of the iconic and beloved series! Watch more: https://youtu.be/M4MUPWBxj1Q | The Drew Barrymore Show

Drew Barrymore and I played 5 Second Rule, and we all learned a lot about each other. | Ellen DeGeneres