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vanderbilt.edu
APC is a tumor suppressor that negatively regulates the Wnt pathway. RKO cells with wild-type (left) and knocked out APC (right). These cells have been stained for beta-catenin
APC is a tumor suppressor that negatively regulates the Wnt pathway. RKO cells with wild-type (left) and knocked out APC (right). These cells have been stained for beta-catenin (yellow) and DNA (blue) Note the intense staining of beta-catenin upon loss of APC.
Jun 12, 2018
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#Adenomatous polyposis coli APC Mutation and Cancer
Although FAP (familial adenomatous polyposis) is a rare and inherited disorder that only makes up 1% of colorectal cancer cases, patients with FAP have a 100% likelihood of developing colon cancer if untreated. Knowing your family history and genetic test results are the most accurate ways to assess cancer risk. The Alliance is on standby to answer any of your questions - 1-833-3BEHIND. | Colorectal Cancer Alliance
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